Registered Nurses, Greenville

$81,400

Local median annual wage in Greenville-Anderson-Greer, SC. Middle half of earners roughly $78,060 to $96,580.

Local salary guide, May 2025, as of May 15, 2026. Cost of living index (2024). Sources stay in methodology · disclaimer.

vs US median
−16.6%
US median
$97,550
Cost of living (93.3) Based on U.S. Bureau of Economic Analysis data. Scores over 100 mean a city is more expensive than the U.S. national average.
93.3
Local pay range The middle 50% of earners in this city make between these amounts, based on official U.S. Bureau of Labor Statistics surveys.
$78,060 to $96,580
Local jobs in field Approximate number of people working in this role locally, not a count of open positions.
9,730
Job code
29-1141

Registered Nurses in Greenville pay a median $81,400 (May 2025), 16.6% below the US median of $97,550. At local prices (index 93.3), that median buys about what $87,245 buys at US-average prices.

What that pay buys

$81,400 in Greenville buys about what $87,245 buys at US-average prices (cost of living index 93.3, 2024). Housing & rent index is 76.8 vs overall 93.3 (US average = 100, 2024).

Registered Nurses in nearby metros

Metro Median Local pay range Cost of living
Greenville $81,400 $78,060 to $96,580 93.3
Louisville $84,850 $77,870 to $97,710 93.1
San Francisco $186,610 $137,120 to $215,630 115.6
Tulsa $84,790 $79,950 to $99,580 89.2

Local salary guide May 2025 where published for the metro.

FAQ

What is the median salary for Registered Nurses in Greenville?
The median annual wage for Registered Nurses in Greenville-Anderson-Greer, SC is $81,400 (May 2025 local salary guide).
How does Greenville pay compare to the US median for Registered Nurses?
Local median pay is 16.6% below the national median of $97,550.
How does cost of living change what that wage buys?
The cost of living index for Greenville is 93.3 (US average = 100, 2024). The local median of $81,400 has about the same buying power as $87,245 at US-average prices.
How current is this data?
Wages use the local salary guide for May 2025. Price levels use the 2024 cost of living index. See methodology for source details.

What this covers

Includes

  • Cost of living index for everyday expenses (housing, groceries & goods, services)
  • Local salary guide: median pay, typical pay range, and jobs in the field where published
  • Target salary math so you keep the same standard of living after a move
  • Approximate single-filer state income tax take-home on compare pages (see rate sources on the page)

Does not include

  • Local city taxes, credits, filing-status variants, or tax advice
  • Childcare, healthcare premiums, or leave benefits
  • Job openings. “Local jobs in field” is how many people work in the role, not hiring demand

Technical source names (RPP, OEWS) and formulas live on the methodology page.

Local pay figures and cost of living indexes come from official government surveys. See methodology and disclaimer.